We were able to conclude that the Cassandra instances were prone to data loss that had Replication Factor set to 1. The RF= 1 induces a risk of data loss when the node goes away suddenly.
We recommend customers to set RF > 1 for their Cassandra instances as it is the best practice.
Also, it is generally advised to use the NetworkTopologyStrategy replication strategy when creating keyspaces to ensure replicas of your data are distributed on nodes in different Availability Zones (AZ) within the service's selected cloud.